A system (1) for the management of personal data (3) relative to a user by maintaining personal privacy, comprising a Discontinuity Engine Interface (4) configured for receiving identification data (2) of the user and receiving encrypted personal data (3) of the user. The system uses separation of information domains to achieve the maximum privacy, different system components have only parts of the information as they manage information or encrypted, obfuscated or anonymous data also in combination. This separation between services and the way information are accessed permit to guarantee the maximum privacy against direct and indirect identification of the client. This level of security is permitted by pervasive cryptography starting from encapsulating data from the originator: client or analysis laboratory.