A first communication device generates and transmits a wakeup packet configured to cause a wakeup radio of a second communication device to prompt a wireless local area network (WLAN) network interface device of the second communication device to transition from a low power state to an active state. The wakeup packet is generated to include i) a WLAN legacy preamble, ii) a wakeup radio (WUR) preamble, and iii) a data portion. The data portion comprises a plurality of time segments, each time segment corresponds to a respective information bit. The data portion is generated to include a respective prefix inserted prior to each time segment corresponding to the respective bit to mitigate intersymbol interference at a receiver caused at least by multipath effects.