Invention Grant
- Patent Title: Inhibitor for retinochoroidal disorders
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Application No.: US14892536Application Date: 2014-05-21
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Publication No.: US10702502B2Publication Date: 2020-07-07
- Inventor: Kazuhiro Kimura
- Applicant: Yamaguchi University
- Applicant Address: JP Yamaguchi
- Assignee: YAMAGUCHI UNIVERSITY
- Current Assignee: YAMAGUCHI UNIVERSITY
- Current Assignee Address: JP Yamaguchi
- Agency: Clark & Elbing LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@65869ea4
- International Application: PCT/JP2014/002667 WO 20140521
- International Announcement: WO2014/188716 WO 20141127
- Main IPC: A61K31/415
- IPC: A61K31/415 ; A61K9/06 ; A61K9/08 ; A61K9/00 ; A61K47/44 ; A61K47/26 ; A61K9/20

Abstract:
The present invention addresses the problem of providing an inhibitor for retinochoroidal disorders, in particular, an inhibitor for retinochoroidal scar formation and retinochoroidal atrophy in an epiretinal, intraretinal or subretinal tissue. This problem can be solved by preparing an inhibitor for retinochoroidal disorders which comprises, as an active ingredient, (E)-4-(2-{3-[(1H-pyrazol-1-yl)methyl]-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-yl}vinyl)benzoic acid, an ester thereof or a salt of the same. The inhibitor for retinochoroidal disorders can inhibit collagen atrophy of retinal pigment epithelium cells, fibroblasts, glial cells and the like and thus inhibit retinochoroidal disorders.
Public/Granted literature
- US20160120843A1 INHIBITOR FOR RETINOCHOROIDAL DISORDERS Public/Granted day:2016-05-05
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