Invention Grant
- Patent Title: Ship inhibition to induce activation of natural killer cells
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Application No.: US15319326Application Date: 2015-06-17
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Publication No.: US10702538B2Publication Date: 2020-07-07
- Inventor: William Kerr , Matthew Gumbleton
- Applicant: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
- Applicant Address: US NY Syracuse
- Assignee: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
- Current Assignee: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
- Current Assignee Address: US NY Syracuse
- Agency: Lathrop GPM LLP
- International Application: PCT/US2015/036246 WO 20150617
- International Announcement: WO2015/195812 WO 20151223
- Main IPC: A61K31/56
- IPC: A61K31/56 ; A61K9/19 ; A61K9/00 ; A61K31/4045 ; A61K31/565 ; A61K31/435 ; A61K31/568 ; C12N15/113 ; A61K31/575

Abstract:
The present invention relates to the use of SHIP1 inhibitors and pan-SHIP1/2 inhibitors in various methods, including, without limitation, a method of inhibiting SHIP to induce broad activation of natural killer (NK) cells to treat various diseases.
Public/Granted literature
- US20170151262A1 SHIP INHIBITION TO INDUCE ACTIVATION OF NATURAL KILLER CELLS Public/Granted day:2017-06-01
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