Invention Grant
- Patent Title: Stable neural stem cells comprising an exogenous polynucleotide coding for a growth factor and methods of use thereof
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Application No.: US15624959Application Date: 2017-06-16
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Publication No.: US10702555B2Publication Date: 2020-07-07
- Inventor: Thomas Hazel , Karl K. Johe
- Applicant: Neuralstem, Inc.
- Applicant Address: US MD Germantown
- Assignee: NEURALSTEM, INC.
- Current Assignee: NEURALSTEM, INC.
- Current Assignee Address: US MD Germantown
- Agency: Morgan, Lewis & Bockius LLP
- Agent Christopher J. Betti
- Main IPC: C12N5/22
- IPC: C12N5/22 ; A61K35/30 ; A61K38/30 ; C12N5/0797 ; C12N5/079 ; C12N5/10 ; A61K48/00 ; C07K14/65
Abstract:
The present disclosure provides a human neural stem cell comprising an exogenous polynucleotide coding for a growth factor such as IGF-1. Also disclosed are methods of using the human neural stem cells for the treatment of neurodegenerative diseases or disorders including, for example, ALS.
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