Invention Grant
- Patent Title: Compositions containing protein loaded exosome and methods for preparing and delivering the same
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Application No.: US15803338Application Date: 2017-11-03
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Publication No.: US10702581B2Publication Date: 2020-07-07
- Inventor: Chulhee Choi , Nambin Yim , Won Do Heo , Seung-Wook Ryu , Hojun Choi , Kyungsun Choi
- Applicant: CELLEX LIFE SCIENCES, INCORPORATED
- Applicant Address: KR Daejeon
- Assignee: ILIAS BIOLOGICS INC.
- Current Assignee: ILIAS BIOLOGICS INC.
- Current Assignee Address: KR Daejeon
- Agency: Lucas & Mercanti, LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@7eeb2ff7 com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@6dcc9cbc com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@6eba9ad2 com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@1972f20a com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@3ec1e244 com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@3761a05c com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@d37c068 com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@3db8166
- Main IPC: C12N15/62
- IPC: C12N15/62 ; C12N15/85 ; A61K47/69 ; A61K38/17 ; C07K16/28 ; C12P21/02 ; C07K16/18 ; C07K14/705 ; A61K38/00
Abstract:
The present invention relates to a method for the mass-production of exosome comprising a cargo protein, a vector for preparing the exosome, exosome including a cargo protein prepared by the method, and a method for loading the cargo protein to cytosol by using the exosome prepared thereby. According to the method for preparing an exosome comprising a cargo protein provided by the present invention, the exosome loaded with a cargo protein can be produced with a high yield, so that it can be used broadly in the treatment of disease using the exosome.
Public/Granted literature
- US20180117117A1 Compositions containing protein loaded exosome and methods for preparing and delivering the same Public/Granted day:2018-05-03
Information query
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