Invention Grant
- Patent Title: Method for producing 5-hydroxypiperidine-2-carboxylic acid
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Application No.: US15965289Application Date: 2018-04-27
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Publication No.: US10703719B2Publication Date: 2020-07-07
- Inventor: Jun Takehara , Masato Murai , Takashi Ohtani , Tomoko Maeda , Tsugihiko Hidaka
- Applicant: API CORPORATION
- Applicant Address: JP Tokyo
- Assignee: API CORPORATION
- Current Assignee: API CORPORATION
- Current Assignee Address: JP Tokyo
- Agency: Greenblum & Bernstein, P.L.C.
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@1ba941b1
- Main IPC: C07D211/60
- IPC: C07D211/60 ; C07C309/66 ; C07C233/47 ; C07D498/08

Abstract:
A method for producing (2S,5S)/(2R,5R)-5-hydroxypiperidine-2-carboxylic acid represented by the formula (10) below: the method including removing the protecting group from the hydroxyl group in a compound represented by formula (7) below: (wherein P represents a protecting group, R3 represents an alkyl group containing 1 to 4 carbon atoms, and A represents an alkyl group containing 1 to 10 carbon atoms, an aryl group containing 6 to 12 carbon atoms, an alkyloxy group containing 1 to 4 carbon atoms, or an aralkyloxy group containing 7 to 20 carbon atoms) to synthesize a compound represented by formula (8) below: (wherein R3 represents an alkyl group containing 1 to 4 carbon atoms, and A represents an alkyl group containing 1 to 10 carbon atoms, an aryl group containing 6 to 12 carbon atoms, an alkyloxy group containing 1 to 4 carbon atoms, or an aralkyloxy group containing 7 to 20 carbon atoms).
Public/Granted literature
- US20180244619A1 METHOD FOR PRODUCING 5-HYDROXYPIPERIDINE-2-CARBOXYLIC ACID Public/Granted day:2018-08-30
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