Invention Grant
- Patent Title: Oxadiazole cyclic peptides
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Application No.: US15760533Application Date: 2016-09-16
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Publication No.: US10703779B2Publication Date: 2020-07-07
- Inventor: Andrei Yudin , John R. Frost
- Applicant: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
- Applicant Address: CA Toronto
- Assignee: The Governing Council of the University of Toronto
- Current Assignee: The Governing Council of the University of Toronto
- Current Assignee Address: CA Toronto
- Agency: Norton Rose Fulbright US LLP
- International Application: PCT/CA2016/000234 WO 20160916
- International Announcement: WO2017/045063 WO 20170323
- Main IPC: C07K7/64
- IPC: C07K7/64 ; C07K1/02 ; C07D498/18 ; C07K7/06
Abstract:
The present invention relates to cyclic amino acid molecules, in particular 1,3,4-oxadiazole containing macrocyclic peptides, and a process to produce the same. The process involves the macrocyclization of amino acids or linear peptides. Specifically, the process comprises reacting an amino acid molecule with an isocyano-iminophosphorane and an aldehyde or a ketone.
Public/Granted literature
- US20180251496A1 OXADIAZOLE CYCLIC PEPTIDES Public/Granted day:2018-09-06
Information query
