Invention Grant
- Patent Title: Methods and compositions for treating multiple sclerosis
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Application No.: US16026482Application Date: 2018-07-03
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Publication No.: US10703811B2Publication Date: 2020-07-07
- Inventor: Robert W. Keane , W. Dalton Dietrich , Juan Pablo De Rivero Vaccari , Helen M. Bramlett , Roberta Brambilla
- Applicant: University of Miami
- Applicant Address: US FL Miami
- Assignee: UNIVERSITY OF MIAMI
- Current Assignee: UNIVERSITY OF MIAMI
- Current Assignee Address: US FL Miami
- Agency: Cooley LLP
- Main IPC: C07K16/24
- IPC: C07K16/24 ; A61P25/28 ; A61P29/00 ; C07K16/18 ; A61P11/00 ; A61P25/00 ; A61K31/727 ; A61K39/395 ; A61P25/14 ; A61P37/06 ; A61K39/00
Abstract:
The compositions and methods described herein include agents that inhibit inflammasome signaling in the mammal such as antibodies directed against inflammasome components used alone or in combination with extracellular vesicle uptake inhibitor(s). Also described herein are compositions and methods of use thereof for treating multiple sclerosis.
Public/Granted literature
- US20190002550A1 METHODS AND COMPOSITIONS FOR TREATING MULTIPLE SCLEROSIS Public/Granted day:2019-01-03
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