Low cytotoxicity compositions are disclosed, most particularly for use in adhesive medical products such as wound dressings (100) and medical skin coverings including surgical incision drapes, bacterial barriers without a wound pad for covering wounds and skin closure products. Methods of treatment are also disclosed that use the adhesive medical products, for example on patients with an injury or a long-term medical condition requiring repeated application of dressings, on patients undergoing surgery, on patients after surgery and/or injury requiring a skin covering, and skin closure methods.