Invention Grant
- Patent Title: Methods and compositions for increased double stranded RNA production
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Application No.: US16084545Application Date: 2017-03-09
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Publication No.: US10704045B2Publication Date: 2020-07-07
- Inventor: John L. Killmer , Patrick D. McLaughlin , Juan Pedro Humberto Arhancet
- Applicant: APSE, INC.
- Applicant Address: US MO St. Louis
- Assignee: APSE, INC.
- Current Assignee: APSE, INC.
- Current Assignee Address: US MO St. Louis
- Agency: Polsinelli PC
- Agent Christopher M. Cabral
- International Application: PCT/US2017/021661 WO 20170309
- International Announcement: WO2017/160600 WO 20170921
- Main IPC: C12N15/113
- IPC: C12N15/113 ; C12N15/11 ; C07K14/005
Abstract:
Methods and materials for improved in vivo production of dsRNA are presented. Yields of dsRNA are significantly increased in the presence of capsid protein. The improved yield of dsRNA is not dependent on the presence of specific cognate binding sites for capsid protein associated with the dsRNA, but is dependent on capsid protein.
Public/Granted literature
- US20190093108A1 Methods and Compositions for Increased Double Stranded RNA Production Public/Granted day:2019-03-28
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