Invention Grant
- Patent Title: Lin28/let-7 crystal structures, purification protocols, and molecular probes suitable for screening assays and therapeutics
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Application No.: US15984109Application Date: 2018-05-18
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Publication No.: US10704049B2Publication Date: 2020-07-07
- Inventor: Piotr Sliz , Yunsun Nam
- Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- Applicant Address: US MA Cambridge
- Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- Current Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- Current Assignee Address: US MA Cambridge
- Agency: Nixon Peabody LLP
- Agent David S. Resnick; Ravinderjit Braich
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K45/06 ; A61K47/60 ; C07K14/47 ; A61K47/64 ; C07H21/02 ; A61K48/00 ; A61K31/7105 ; A61K31/7115 ; A61K31/712 ; A61K31/713
Abstract:
The invention provides compositions and methods for regulating microRNA (miRNA) biogenesis. The invention also relates to compositions and methods for treating or preventing cancer in a subject in need thereof.
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