- Patent Title: Method of producing heparan sulfate having anticoagulant activity
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Application No.: US16018269Application Date: 2018-06-26
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Publication No.: US10704068B2Publication Date: 2020-07-07
- Inventor: Yuriko Tokura
- Applicant: AJINOMOTO CO., INC.
- Applicant Address: JP Tokyo
- Assignee: AJINOMOTO CO., INC.
- Current Assignee: AJINOMOTO CO., INC.
- Current Assignee Address: JP Tokyo
- Agency: Cermak Nakajima & McGowan LLP
- Agent Shelly Guest Cermak
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@5bbea7bb
- Main IPC: C12P19/04
- IPC: C12P19/04 ; C12P19/26 ; A61K31/727 ; C12N15/09 ; C12N9/14 ; A61P7/02
Abstract:
The present invention provides a method of producing a heparan sulfate having an anticoagulant activity. Specifically, the present invention provides the method of producing a heparan sulfate having a desired molecular weight, by partially N-deacetylating a heparosan followed by depolymerizing the heparosan by heparinase III, and converting the produced low molecular weight product into heparan sulfate having an anticoagulant activity.
Public/Granted literature
- US20180298411A1 Method of Producing Heparan Sulfate Having Anticoagulant Activity Public/Granted day:2018-10-18
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