Invention Grant
- Patent Title: Determination of small-molecule thiols and disulfides: protein bound cys and total cysteine as biomarkers of oxidative stress
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Application No.: US15328694Application Date: 2015-07-27
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Publication No.: US10705093B2Publication Date: 2020-07-07
- Inventor: Xiaoyun Fu , Shelby A. Cate , Jose Aron Lopez , Junmei Chen , Barbara A. Konkle
- Applicant: Bloodworks
- Applicant Address: US WA Seattle
- Assignee: Bloodworks
- Current Assignee: Bloodworks
- Current Assignee Address: US WA Seattle
- Agency: Lee & Hayes PC
- Agent C. Rachal Winger; Thu Nguyen
- International Application: PCT/US2015/042318 WO 20150727
- International Announcement: WO2016/015060 WO 20160128
- Main IPC: G01N33/68
- IPC: G01N33/68 ; A61K9/00 ; A61K31/19 ; G01N30/88
Abstract:
Compositions and methods for determining the level of thiol and disulfide containing molecules in a sample are provided. The compositions and methods can be used to determine the level of oxidative stress in a subject with or without antioxidant treatment. Also provided are biomarkers of oxidative stress.
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