Invention Grant
- Patent Title: Mucoadhesive buccal film having a dual release carrier system
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Application No.: US16775304Application Date: 2020-01-29
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Publication No.: US10709662B1Publication Date: 2020-07-14
- Inventor: Tarek A. Ahmed , Alaa O. Bawazir , Abdelsattar M. Omar , Martin K. Safo
- Applicant: King Abdulaziz University , Virginia Commonwealth University
- Applicant Address: SA Jeddah US VA Richmond
- Assignee: King Abdulaziz University,Virginia Commonwealth University
- Current Assignee: King Abdulaziz University,Virginia Commonwealth University
- Current Assignee Address: SA Jeddah US VA Richmond
- Agency: W & C, IP
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61K47/40 ; A61K47/32 ; A61K9/107 ; A61K47/24 ; A61K31/351 ; A61K9/14 ; A61P1/16
Abstract:
Mucoadhesive buccal films comprising a statin-hydroxypropyl-beta-cyclodextrin inclusion complex and a statin-loaded mixed micelle composition, wherein the ratio of the mixed micelle composition to the inclusion complex is from 2:0.5 to 2:1.5 are provided. Methods of improving permeation of a statin across mucosal tissue by administering the film to a subject are also provided.
Information query
