Invention Grant
- Patent Title: Antithrombotic metallic material
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Application No.: US15562324Application Date: 2016-03-31
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Publication No.: US10709822B2Publication Date: 2020-07-14
- Inventor: Koji Kadowaki , Masaki Fujita , Yuka Sakaguchi , Kazuhiro Tanahashi
- Applicant: Toray Industries, Inc.
- Applicant Address: JP Tokyo
- Assignee: Toray Industries, Inc.
- Current Assignee: Toray Industries, Inc.
- Current Assignee Address: JP Tokyo
- Agency: DLA Piper LLP (US)
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@721abd1c
- International Application: PCT/JP2016/060679 WO 20160331
- International Announcement: WO2016/159243 WO 20161006
- Main IPC: A61L33/00
- IPC: A61L33/00 ; A61L33/06 ; A61L33/04 ; A61L31/10

Abstract:
An antithrombogenic metallic material includes a metallic material whose surface is coated with a coating material, the coating material containing: a phosphonic acid derivative or a catechol derivative; a polymer containing, as a constituent monomer, a compound selected from the group consisting of alkyleneimines, vinylamines, allylamines, lysine, protamine, and diallyldimethylammonium chloride; and an anionic compound containing a sulfur atom and having anticoagulant activity; the polymer being covalently bound to the phosphonic acid derivative or the catechol derivative, the phosphonic acid derivative or the catechol derivative being bound to the metallic material through a phosphonic acid group or a catechol group thereof, wherein the abundance ratio of nitrogen atoms to the abundance of total atoms as measured by X-ray photoelectron spectroscopy (XPS) on the surface is 4.0 to 13.0 atomic percent.
Public/Granted literature
- US20180344906A1 ANTITHROMBOTIC METALLIC MATERIAL Public/Granted day:2018-12-06
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