Invention Grant
- Patent Title: Oxadiazole transient receptor potential channel inhibitors
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Application No.: US16355352Application Date: 2019-03-15
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Publication No.: US10710994B2Publication Date: 2020-07-14
- Inventor: Jack Alexander Terrett , Huifen Chen , Lea Constantineau-Forget , Robin Larouche-Gauthier , Luce Lépissier , Francis Beaumier , Martin Déry , Chantal Grand-Maître , Claudio Sturino , Matthew Volgraf , Elisia Villemure
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Robert C. Hall
- Main IPC: A61P23/00
- IPC: A61P23/00 ; A61P11/00 ; A61P29/00 ; A61P25/00 ; C07D471/04 ; C07D473/30 ; C07D487/04 ; C07D413/14 ; C07D498/04 ; C07D513/04 ; A61K31/427
Abstract:
The invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof wherein A, X, R1, R4 and n are as defined herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.
Public/Granted literature
- US20190284179A1 OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS Public/Granted day:2019-09-19
Information query
IPC分类:
| A | 人类生活必需 |
| A61 | 医学或兽医学；卫生学 |
| A61P | 化合物或药物制剂的特定治疗活性 |
| A61P23/00 | 麻醉剂 |
