Invention Grant
- Patent Title: Indoline analogs and uses thereof
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Application No.: US16430234Application Date: 2019-06-03
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Publication No.: US10711008B2Publication Date: 2020-07-14
- Inventor: Stephen E. Webber
- Applicant: Oncternal Therapeutics, Inc.
- Applicant Address: US CA San Diego
- Assignee: Oncternal Therapeutics, Inc.
- Current Assignee: Oncternal Therapeutics, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D405/06 ; C07D209/38 ; C07D209/40 ; C07D401/06 ; C07D209/34 ; C07D409/06 ; C07D413/06 ; C07D417/06 ; C07D403/06

Abstract:
Indoline derivative compounds that act as EWS-FLI1 transcription factor inhibitors are provided. Also provided are pharmaceutical compositions of the indoline derivatives, methods of synthesizing the same, methods of treating using same, and assays for identifying the inhibitors of EWS-FLI1 oncoprotein.
Public/Granted literature
- US20190337951A1 INDOLINE ANALOGS AND USES THEREOF Public/Granted day:2019-11-07
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