A resistive memory device includes: a normal cell array suitable for including a plurality of memory cells and generating a cell current according to a resistance state of a memory cell selected based on an input address; a reference cell array suitable for including a plurality of sub-arrays each including a predetermined number of memory cells, and generating a reference current according to a combination of resistance states of memory cells of a sub-array, the sub-array being selected based on a reference selection signal; a sense amplifier circuit suitable for sensing and amplifying a signal indicative of data of the selected memory cell based on the cell current and the reference current during a read operation; and a reference cell selector suitable for generating the reference selection signal, the sub-array in the reference cell array corresponding to a position of the selected memory cell in the normal cell array.