Invention Grant
- Patent Title: Compositions and methods of enhancing immune responses to enteric pathogens
-
Application No.: US16531893Application Date: 2019-08-05
-
Publication No.: US10716840B2Publication Date: 2020-07-21
- Inventor: Lisa Bielke , Sherryll Layton , Billy Hargis , Neil R. Pumford , Olivia B. Faulkner , Luc Berghman , Daad Abi-Ghanem
- Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS , THE TEXAS A&M UNIVERSITY SYSTEM
- Applicant Address: US AR Little Rock US TX College Station
- Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS,THE TEXAS A&M UNIVERSITY SYSTEM
- Current Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS,THE TEXAS A&M UNIVERSITY SYSTEM
- Current Assignee Address: US AR Little Rock US TX College Station
- Agency: Quarles & Brady LLP
- Main IPC: C07H21/02
- IPC: C07H21/02 ; A61K39/00 ; A61K39/02 ; A61K39/112 ; A61K39/108 ; C07K16/12 ; C12N15/85
Abstract:
Vaccine vectors capable of eliciting an immune response to enteric bacteria and methods of using the same are provided. The vaccine vectors include a polynucleotide encoding a PAL polypeptide. The PAL polypeptide may be expressed on the surface of the vaccine vector. The vaccine vector may also include a second polypeptide encoding an immunostimulatory polypeptide such as a CD154 polypeptide or an HMGB1 polypeptide.
Public/Granted literature
- US20190351042A1 COMPOSITIONS AND METHODS OF ENHANCING IMMUNE RESPONSES TO ENTERIC PATHOGENS Public/Granted day:2019-11-21
Information query
