Invention Grant
- Patent Title: Stabilized human immunodeficiency virus (HIV) clade C envelope (Env) trimer vaccines and methods of using same
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Application No.: US15026391Application Date: 2014-10-03
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Publication No.: US10716845B2Publication Date: 2020-07-21
- Inventor: Dan H. Barouch , Christine Bricault
- Applicant: Beth Israel Deaconess Medical Center, Inc.
- Applicant Address: US MA Boston
- Assignee: Beth Israel Deaconess Medical Center, Inc.
- Current Assignee: Beth Israel Deaconess Medical Center, Inc.
- Current Assignee Address: US MA Boston
- Agency: Clark & Elbing LLP
- International Application: PCT/US2014/059093 WO 20141003
- International Announcement: WO2015/051270 WO 20150409
- Main IPC: A61K39/12
- IPC: A61K39/12 ; A61K39/21 ; C07K14/16 ; C12N7/00 ; A61K39/00
Abstract:
The invention features stabilized human immunodeficiency virus (H IV) clade C envelope (Env) trimers. The invention also features vaccines, nucleic acids, and vectors to deliver and/or facilitate production of the stabilized HIV clade C Env trimers. In addition, the invention features methods of making and using the stabilized HIV clade C Env trimers of the invention.
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