Invention Grant
- Patent Title: Haloallylamine indole and azaindole derivative inhibitors of lysyl oxidases and uses thereof
-
Application No.: US16076979Application Date: 2017-02-10
-
Publication No.: US10717733B2Publication Date: 2020-07-21
- Inventor: Alison Dorothy Findlay , Craig Ivan Turner , Mandar Deodhar , Jonathan Stuart Foot , Wolfgang Jarolimek , Wenbin Zhou , Alan Duncan Robertson
- Applicant: PHARMAXIS LTD.
- Applicant Address: AU Frenchs Forest, New South Wales
- Assignee: Pharmaxis Ltd.
- Current Assignee: Pharmaxis Ltd.
- Current Assignee Address: AU Frenchs Forest, New South Wales
- Agency: Cooper & Dunham LLP
- Agent Gary J. Gershik
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@5bc185eb com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@73afaea4
- International Application: PCT/AU2017/000039 WO 20170210
- International Announcement: WO2017/136870 WO 20170817
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D487/04 ; A61K45/06 ; C07D209/42 ; A61P1/16 ; A61P13/12 ; A61P11/00 ; A61K31/4025 ; A61K31/4045 ; A61K31/41 ; A61K31/4245 ; A61K31/437 ; A61K31/4439 ; A61K31/506 ; C07D209/14 ; C07D401/04 ; C07D403/04 ; C07D403/10 ; C07D413/10 ; A61K31/5025 ; A61K31/519 ; C07D209/20 ; C07D209/36
Abstract:
The present invention relates to novel compounds which are capable of inhibiting certain amine oxidase enzymes. These compounds are useful for treatment of a variety of indications, e.g., fibrosis, cancer and/or angiogenesis in human subjects as well as in pets and livestock. In addition, the present invention relates to pharmaceutical compositions containing these compounds, as well as various uses thereof.
Public/Granted literature
- US20190040007A1 HALOALLYLAMINE INDOLE AND AZAINDOLE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF Public/Granted day:2019-02-07
Information query
