Intermediates and methods for the synthesis of halichondrin B analogs

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US10717743B2 Intermediates and methods for the synthesis of halichondrin B analogs 有权

Patent Title: Intermediates and methods for the synthesis of halichondrin B analogs
Application No.: US16284405

Application Date: 2019-02-25
Publication No.: US10717743B2

Publication Date: 2020-07-21
Inventor: Charles E. Chase , Atsushi Endo , Francis G. Fang , Jing Li
Applicant: EISAI R&D MANAGEMENT CO., LTD.
Applicant Address: JP Tokyo
Assignee: EISAI R&D MANAGEMENT CO., LTD.
Current Assignee: EISAI R&D MANAGEMENT CO., LTD.
Current Assignee Address: JP Tokyo
Agency: Clark & Elbing LLP
Main IPC: C07D493/20
IPC: C07D493/20 ; C07D307/28 ; C07D307/33 ; C07D493/08 ; C07D493/18 ; C07D493/04 ; C07D493/22 ; C07D307/20 ; C07D307/26 ; C07D309/16 ; C07D405/06 ; C07D405/14

Abstract:

Methods of synthesizing intermediates useful for the synthesis of halichondrin B analogs are described.

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