Invention Grant
- Patent Title: Polymeric biomaterials derived from monomers comprising hydroxyacids and phenol compounds and their medical uses
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Application No.: US16439232Application Date: 2019-06-12
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Publication No.: US10717810B2Publication Date: 2020-07-21
- Inventor: Durgadas Bolikal , Joachim B. Kohn , Lioubov Kabalnova
- Applicant: Rutgers, The State University of New Jersey , Reva Medical, Inc.
- Applicant Address: US NJ New Brunswick US CA San Diego
- Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY,REVA MEDICAL, INC.
- Current Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY,REVA MEDICAL, INC.
- Current Assignee Address: US NJ New Brunswick US CA San Diego
- Agency: Fox Rothschild LLP
- Main IPC: C08G63/08
- IPC: C08G63/08 ; C08G63/64 ; A61L31/14 ; A61L31/18 ; C08G63/19 ; C08G64/02 ; C08G64/16 ; A61L31/06 ; A61L31/16 ; C08G63/91 ; C08G79/025 ; C08G79/04
Abstract:
The present invention provides new classes of phenolic compounds derived from hydroxyacids and tyrosol or tyrosol analogues, useful as monomers for preparation of biocompatible polymers, and the biocompatible polymers prepared from these monomeric hydroxyacid-phenolic compounds, including novel biodegradable and/or bioresorbable polymers. These biocompatible polymers or polymer compositions with enhanced bioresorbabilty and processability are useful in a variety of medical applications, such as in medical devices and controlled-release therapeutic formulations. The invention also provides methods for preparing these monomeric hydroxyacid-phenolic compounds and biocompatible polymers.
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