Invention Grant
- Patent Title: Compositions and methods for regulating thermogenesis and muscle inflammation using metrnl and metrn
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Application No.: US14762375Application Date: 2014-01-21
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Publication No.: US10717992B2Publication Date: 2020-07-21
- Inventor: Bruce M. Spiegelman , Rajesh R. Rao , Jonathan Z. Long
- Applicant: Dana-Farber Cancer Institute, Inc.
- Applicant Address: US MA Boston
- Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee Address: US MA Boston
- Agency: Foley Hoag LLP
- International Application: PCT/US2014/012243 WO 20140121
- International Announcement: WO2014/116556 WO 20140731
- Main IPC: A61K38/18
- IPC: A61K38/18 ; A61K48/00 ; A61P3/00 ; C07K14/52 ; C12N15/86 ; C12Q1/6876 ; C07K14/47
Abstract:
The invention provides compositions and methods for regulating thermogenesis and muscle inflammation through modulation of Metrnl and/or Metrn activity and/or expression. Also provided are methods for preventing or treating metabolic disorders and muscle inflammation disorders in a subject through modulation of Metrnl and/or Metrn activity and/or expression. Further provided are methods for identifying compounds that are capable of treating metabolic disorders and muscle inflammation disorders by modulating Metrnl and/or Metrn activity and/or expression.
Public/Granted literature
- US20150322460A1 COMPOSITIONS AND METHODS FOR REGULATING THERMOGENESIS AND MUSCLE INFLAMMATION USING METRNL AND METRN Public/Granted day:2015-11-12
Information query
IPC分类:
