Invention Grant
- Patent Title: Methods and compositions for identifying repeating sequences in nucleic acids
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Application No.: US15625326Application Date: 2017-06-16
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Publication No.: US10718016B2Publication Date: 2020-07-21
- Inventor: Joseph J. Regensburger , Aaron J. Sander , Jared M. Schuetter , Daniel M. Bornman , Seth A. Faith , Scott C. Nelson , Brian A. Young
- Applicant: BATTELLE MEMORIAL INSTITUTE
- Applicant Address: US OH Columbus
- Assignee: BATTELLE MEMORIAL INSTITUTE
- Current Assignee: BATTELLE MEMORIAL INSTITUTE
- Current Assignee Address: US OH Columbus
- Agency: Barnes & Thornburg LLP
- Main IPC: G01N33/48
- IPC: G01N33/48 ; G01N33/50 ; C12Q1/6869 ; G16B20/00 ; G16B30/00 ; G16B40/00 ; C12Q1/6809 ; C12N15/10 ; C12Q1/686 ; G06F19/00

Abstract:
Short Tandem Repeats are currently used by law enforcement and others, for example, for the identification of individuals by DNA matching. A method is described herein that uses WPD to classify and identify repeating sequences in nucleotide sequences from the position and frequency information contained within nucleotide sequences. This decomposition allows for the quick classification of nucleotide sequences (i.e., reads) into two different classes, including, for example, one class that contains sequencer reads that contain a repeat motif with non-repeat sequence on either flank, and another class that contains sequencer reads that do not contain any repeat sequence.
Public/Granted literature
- US20170292155A1 METHODS AND COMPOSITIONS FOR IDENTIFYING REPEATING SEQUENCES IN NUCLEIC ACIDS Public/Granted day:2017-10-12
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