The present disclosure relates to an emergency response system having an emergency response system server, a patient database, a communication system, and many patient response devices (PAD) for many patients. Each patient and each PAD are registered at emergency response system server and patient information is stored in patient database. When emergency occurs to a patient carrying PAD, patient presses an emergency button on PAD and PAD initiates an emergency call to emergency dispatch center to notify patient's GPS location and patient information. live emergency responder connects to one or more patient's helping hands and a medical facility to coordinate immediate medical assistance to the patient based on the patient information received and retrieved from the patient database. Patient specific medical assistance instructions are sent to patient, patient takes patient specific emergency medicines stored in PAD. The patient continues to communicate with the live emergency responder until ambulance arrives.