Invention Grant
- Patent Title: Reducing error in predicted genetic relationships
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Application No.: US15519104Application Date: 2015-10-14
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Publication No.: US10720229B2Publication Date: 2020-07-21
- Inventor: Mathew J Barber , Yong Wang , Keith D. Noto , Kenneth G. Chahine , Catherine Ann Ball
- Applicant: Ancestry.com DNA, LLC
- Applicant Address: US UT Lehi
- Assignee: Ancestry.com DNA, LLC
- Current Assignee: Ancestry.com DNA, LLC
- Current Assignee Address: US UT Lehi
- Agency: Fenwick & West LLP
- International Application: PCT/US2015/055579 WO 20151014
- International Announcement: WO2016/061260 WO 20160421
- Main IPC: G16B40/00
- IPC: G16B40/00 ; G16B10/00 ; G06N5/04 ; G06N7/00 ; C12Q1/6881 ; G16B20/40

Abstract:
System, computer program products, and methods are disclosed for estimating a degree of ancestral relatedness between two individuals. The haplotype data for a population of individuals is divided into segment windows based on genetic markers, and matched segments for the haplotype data are generated. Each matched segment having a first cM width that exceeds a threshold cM width is included in counting the matched segments in each segment window. A weight associated with each segment window is estimated based on the count of matched segments in the associated segment window. A weighted sum of per-window cM widths for each matched segment is calculated based on the first cM width and the weights associated with the segment windows of the matched segment. The weighted sum of per-window cM widths are used to estimate a degree of ancestral relatedness between two individuals.
Public/Granted literature
- US20170220738A1 REDUCING ERROR IN PREDICTED GENETIC RELATIONSHIPS Public/Granted day:2017-08-03
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