Invention Grant
- Patent Title: Method for predicting risk of exposure to interstitial fibrosis and tubular atrophy with clusterin
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Application No.: US15810861Application Date: 2017-11-13
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Publication No.: US10725026B2Publication Date: 2020-07-28
- Inventor: Barbara Murphy , Philip J. O'Connell
- Applicant: Icahn School of Medicine at Mount Sinai , Westmead Institute For Medical Research , Western Sydney Local Health District
- Applicant Address: US NY New York AU Westmead AU Westmead
- Assignee: Icahn School of Medicine at Mount Sinai,Westmead Institute For Medical Research,Western Sydney Local Health District
- Current Assignee: Icahn School of Medicine at Mount Sinai,Westmead Institute For Medical Research,Western Sydney Local Health District
- Current Assignee Address: US NY New York AU Westmead AU Westmead
- Agency: Fish & Richardson P.C.
- Main IPC: G01N33/50
- IPC: G01N33/50 ; G01N33/53 ; A61P13/12 ; G01N33/68 ; C07K14/47
Abstract:
A method for identifying a kidney transplant recipient at an increased risk of developing interstitial fibrosis or tubular atrophy which comprises obtaining a post-transplant urine sample from the kidney transplant recipient; measuring the level of clusterin in the urine sample; comparing the level of clusterin in the patient sample to the level of clusterin in a control sample from the urine of a non-fibrotic kidney transplant recipient; diagnosing a kidney transplant recipient with a clusterin level that is significantly higher than the clusterin level in the control as being at an increased risk of developing interstitial fibrosis or tubular atrophy.
Public/Granted literature
- US20180292395A1 METHOD FOR PREDICTING RISK OF EXPOSURE TO INTERSTITIAL FIBROSIS AND TUBULAR ATROPHY WITH CLUSTERIN Public/Granted day:2018-10-11
Information query
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