Invention Grant
- Patent Title: Method and apparatus for mitigating the effect of magnetization transfer in model-based magnetic resonance techniques
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Application No.: US15822474Application Date: 2017-11-27
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Publication No.: US10725132B2Publication Date: 2020-07-28
- Inventor: Martijn Cloos , Tom Hilbert , Tobias Kober
- Applicant: NEW YORK UNIVERSITY , SIEMENS HEALTHCARE GmbH
- Applicant Address: DE Erlangen US NY New York
- Assignee: Siemens Healthcare GmbH,New York University
- Current Assignee: Siemens Healthcare GmbH,New York University
- Current Assignee Address: DE Erlangen US NY New York
- Agency: Schiff Hardin LLP
- Main IPC: G01R33/48
- IPC: G01R33/48 ; G01R33/56 ; G01R33/50

Abstract:
In a magnetic resonance (MR) apparatus, and model-based method, for identifying a nuclear spin-dependent attribute of a subject, MR signals are acquired in multiple repetitions of an MR data acquisition sequence that is changed from repetition-to-repetition so as to deliberately encode effects of magnetization transfer between nuclear spins into the acquired MR signals. A model is generated, composed of at least two molecule pools, in which a single magnetization transfer parameter is used that is derived from the MR signals in which the magnetization transfer is encoded. A nuclear spin-dependent attribute of the subject is then identified, by comparing at least one MR signal evolution from the subject to at least one signal evolution produced by the model.
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