A hybrid attachment mechanism is provided to attach an adjunct to an end effector jaw of a surgical instrument, such as a surgical stapler. The hybrid attachment mechanism can include at least two attachment mechanisms, each configured to inhibit at least one manner of detachment from the end effector jaw. A first attachment mechanism can be configured to inhibit vertical removal of the adjunct. A second attachment mechanism can be configured to inhibit sliding of the adjunct with respect to the jaw. A third attachment mechanism can be configured to inhibit curling of the adjunct upon itself. Each of the attachment mechanisms can operate in concert with the others, allowing the hybrid attachment mechanism to simultaneously inhibit multiple forms of adjunct detachment. The hybrid attachment mechanism can be further configured to decouple from the end effector jaw, permitting deployment of the adjunct at a treatment site.