Invention Grant
- Patent Title: Methods of treating castration-resistant prostate cancer with glucocorticoid receptor antagonists after anticancer therapy
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Application No.: US16374157Application Date: 2019-04-03
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Publication No.: US10729699B2Publication Date: 2020-08-04
- Inventor: Russell Z. Szmulewitz , Suzanne D. Conzen
- Applicant: The University of Chicago
- Applicant Address: US IL Chicago
- Assignee: The University of Chicago
- Current Assignee: The University of Chicago
- Current Assignee Address: US IL Chicago
- Agency: Kilpatrick Townsend & Stockton
- Main IPC: A61K31/567
- IPC: A61K31/567 ; A61K31/4166 ; A61K31/437 ; A61K31/569 ; A61K31/573 ; A61K45/06 ; A61N5/10
Abstract:
Embodiments of the invention are directed to the treatment of subjects with prostate cancer, in particular those with castration resistant prostate cancer, with glucocorticoid receptor antagonists. The prostate cancer may be one that has become resistant to androgen deprivation therapy, for example, by increase in glucocorticoid receptor expression and/or activity.
Public/Granted literature
- US20190255069A1 METHODS OF TREATING CASTRATION-RESISTANT PROSTATE CANCER WITH GLUCOCORTICOID RECEPTOR ANTAGONISTS Public/Granted day:2019-08-22
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