Invention Grant
- Patent Title: Integrated fluidic devices and related methods
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Application No.: US15458288Application Date: 2017-03-14
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Publication No.: US10730041B2Publication Date: 2020-08-04
- Inventor: Alon Singer , Ranjit Prakash
- Applicant: HelixBind, Inc.
- Applicant Address: US MA Marlborough
- Assignee: HelixBind, Inc.
- Current Assignee: HelixBind, Inc.
- Current Assignee Address: US MA Marlborough
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: B01L3/00
- IPC: B01L3/00 ; B01D71/34 ; C12Q1/686 ; B01L7/00 ; B01D63/08 ; B01D69/02

Abstract:
Fluidic devices and related methods are generally provided. The fluidic devices described herein may be useful, for example, for diagnostic purposes (e.g., detection of the presence of one or more disease causing bacteria in a patient sample). Unlike certain existing fluidic devices for diagnostic purposes, the fluidic devices and methods described herein may be useful for detecting the presence of numerous disease causing bacteria in a patient sample substantially simultaneously (e.g., in parallel). In some embodiments, the fluidic devices and methods described herein provide highly sensitive detection of microbes in relatively large fluidic samples (e.g., between 0.5 mL and about 5 mL), as compared to certain existing fluidic detection (e.g., microfluidic) devices and methods. In an exemplary embodiment, increased detection sensitivity of microbial pathogens present in a patient sample (e.g., blood) is performed by selectively removing human nucleic acid prior to sensitive detection of microbial infection. In some embodiments, the fluidic device allows for the identification of microbial pathogens directly from unprocessed blood without having to conduct blood culturing processes.
Public/Granted literature
- US20170259257A1 INTEGRATED FLUIDIC DEVICES AND RELATED METHODS Public/Granted day:2017-09-14
Information query
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