Invention Grant
- Patent Title: Process for producing epoxy alcohol compound
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Application No.: US16636852Application Date: 2018-07-25
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Publication No.: US10730861B2Publication Date: 2020-08-04
- Inventor: Kenichi Ando , Yohei Tanaka , Koh Kawami
- Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED
- Applicant Address: JP Chuo-ku
- Assignee: SUMITOMO CHEMICAL COMPANY, LIMITED
- Current Assignee: SUMITOMO CHEMICAL COMPANY, LIMITED
- Current Assignee Address: JP Chuo-ku
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@1749b15e
- International Application: PCT/JP2018/027835 WO 20180725
- International Announcement: WO2019/031240 WO 20190214
- Main IPC: C07D405/06
- IPC: C07D405/06 ; C07D301/03 ; C07D303/04

Abstract:
A compound represented by formula (II): (where Ar represents a phenyl group optionally substituted by 1 to 3 substituents selected from the group consisting of a halogen atom and a trifluoromethyl group, and R represents a hydrogen atom or an alkyl group having 1 to 12 carbon atoms) is produced by step A: reacting trimethyl oxosulfonium salt or trimethyl sulfonium salt with a base in a solvent, and removing the resulting solid to obtain a trimethyl oxosulfonium ylide solution or a trimethyl sulfonium ylide solution; and step B: reacting a compound represented by formula (I): and the solution obtained in step A, and the compound represented by formula (II) can be derived to a compound represented by formula (V): that is useful for production of an antifungal agent.
Public/Granted literature
- US20200172520A1 PROCESS FOR PRODUCING EPOXY ALCOHOL COMPOUND Public/Granted day:2020-06-04
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