Invention Grant
- Patent Title: Production method for artificial cancer stem cell and induced differentiation method therefor
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Application No.: US14122634Application Date: 2012-05-24
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Publication No.: US10731134B2Publication Date: 2020-08-04
- Inventor: Akihide Ryo , Mayuko Nishi
- Applicant: Akihide Ryo , Mayuko Nishi
- Applicant Address: JP Kanagawa
- Assignee: Public University Corporation Yokohama City University
- Current Assignee: Public University Corporation Yokohama City University
- Current Assignee Address: JP Kanagawa
- Agency: Morgan, Lewis & Bockius LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@2f52d5ee
- International Application: PCT/JP2012/063302 WO 20120524
- International Announcement: WO2012/165287 WO 20121206
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/095 ; G01N33/50
Abstract:
It is intended to provide a cancer stem cell and a method for preparing the same. The present invention provides a method for preparing a pluripotent cancer stem cell, comprising transferring Oct3/4, Sox2, Klf4, and c-Myc genes to an immortalized epithelial cell. The present invention also provides a pluripotent cancer stem cell as prepared by the above method.
Public/Granted literature
- US20140120571A1 PRODUCTION METHOD FOR ARTIFICIAL CANCER STEM CELL AND INDUCED DIFFERENTIATION METHOD THEREFOR Public/Granted day:2014-05-01
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