Invention Grant
- Patent Title: Methods and compositions for stabilizing trans-splicing intein modified proteases
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Application No.: US15519602Application Date: 2015-10-28
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Publication No.: US10731143B2Publication Date: 2020-08-04
- Inventor: R. Michael Raab , Binzhang Shen , Gabor Lazar
- Applicant: AGRIVIDA, INC.
- Applicant Address: US MA Woburn
- Assignee: AGRIVIDA, INC.
- Current Assignee: AGRIVIDA, INC.
- Current Assignee Address: US MA Woburn
- Agency: Volpe and Koenig, P.C.
- International Application: PCT/US2015/057862 WO 20151028
- International Announcement: WO2016/069774 WO 20160506
- Main IPC: C12N9/54
- IPC: C12N9/54 ; C11D3/386 ; C07K14/00
Abstract:
Methods for producing a trans-splicing intein-modified protease with enhanced solubility and regulating its activity are described. Intein-modified proteases having enhanced solubility and polynucleotides encoding the same are provided. Methods of storing trans-splicing proteases are also described.
Public/Granted literature
- US20180298368A1 METHODS AND COMPOSITIONS FOR STABILIZING TRANS-SPLICING INTEIN MODIFIED PROTEASES Public/Granted day:2018-10-18
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