Invention Grant
- Patent Title: Engineered proline hydroxylase polynucleotides and methods
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Application No.: US16446866Application Date: 2019-06-20
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Publication No.: US10731189B2Publication Date: 2020-08-04
- Inventor: Haibin Chen , Yong Koy Bong , Fabien L. Cabirol , Anupam Gohel Prafulchandra , Tao Li , Jeffrey C. Moore , Martina Quintanar-Audelo , Yang Hong , Steven J. Collier , Derek Smith
- Applicant: Codexis, Inc.
- Applicant Address: US CA Redwood City
- Assignee: Codexis, Inc.
- Current Assignee: Codexis, Inc.
- Current Assignee Address: US CA Redwood City
- Agency: Codexis, Inc.
- Main IPC: C12N11/10
- IPC: C12N11/10 ; C12P17/12 ; C12P17/18 ; C12N9/02 ; C12P13/24 ; C12P13/04
Abstract:
The present disclosure provides engineered proline hydroxylase polypeptides for the production of hydroxylated compounds, polynucleotides encoding the engineered proline hydroxylases, host cells capable of expressing the engineered proline hydroxylases, and methods of using the engineered proline hydroxylases to prepare compounds useful in the production of active pharmaceutical agents.
Public/Granted literature
- US20190323046A1 BIOCATALYSTS AND METHODS FOR HYDROXYLATION OF CHEMICAL COMPOUNDS Public/Granted day:2019-10-24
Information query
