A system (100) and method for generating machining control data of a numerical control machine tool. The system (100) comprises a server (10) and at least one terminal device (30). The server (10) is installed with computer-aided manufacturing software, a numerical control machine tool model library and a cutter and fixture library. The terminal device (30) is connected to the server (10) through the Internet (20) to generate machining program data of a part model and/or to carry out machining simulation of a part model. The method for generating machining control data of a numerical control machine tool comprises: sending a part model file to the server (10) through the Internet (20); and generating program code that can be executed by the numerical control machine tool. The system (100) and the method have the beneficial technical effects of being convenient to operate, low in cost and flexible and easy to use and so on.