In accordance with embodiments of the present disclosure, an information handling system may include a motherboard, a plurality of information handling resources communicatively coupled to the motherboard, a socket communicatively coupled to the motherboard and configured to receive one of a plurality of different types of interposers, wherein each of the plurality of interposers is configured to provide routing of electrical signals between the socket and a respective system on a chip communicatively coupled to such interposer, and a configuration module. The configuration module may be configured to receive identifying information associated with an interposer, of the plurality of interposers, communicatively coupled to the socket and based on the identifying information, configure the plurality of information handling resources for interoperability with a system on a chip communicatively coupled to the interposer.