In a general aspect, a quantum logic control sequence is generated for a quantum information processor. In some aspects, a quantum computation to be performed by a quantum information processor is identified. The quantum information processor includes data qubits and is configured to apply entangling quantum logic operations to respective pairs of the data qubits. A graph representing the quantum information processor is defined. The graph includes vertices and edges; the vertices represent the data qubits, and the edges represent the entangling quantum logic operations. A quantum logic control sequence is generated based on the graph. The quantum logic control sequence includes a sequence of quantum logic operations configured to perform the quantum computation when executed by the quantum information processor.