A method and a system for anatomical site relocalisation using dual data synchronisation. Method for repositioning, possibly several times, at a specific location, which has been already explored during a first or “reference exploration”, a flexible endoscope during one or more successive endoluminal or extraluminal subsequent or “new exploration”, or similar procedures, wherein the repositioning is realized either manually, by a human user, or automatically, by a robotic system, from or by way of a synchronisation process between a “new exploration” flexible endoscope video and the “reference exploration” flexible endoscope video displayed in parallel on or in two different windows, on one or more screens.