Invention Grant
- Patent Title: Anti-methanogenic lovastatin analogs or derivatives and uses thereof
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Application No.: US15560145Application Date: 2016-03-31
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Publication No.: US10736871B2Publication Date: 2020-08-11
- Inventor: Mark Pimentel , Vince Wacher
- Applicant: Cedars-Sinai Medical Center , Synthetic Biologics, Inc.
- Applicant Address: US CA Los Angeles US MD Rockville
- Assignee: Cedars-Sinai Medical Center,Synthetic Biologics, Inc.
- Current Assignee: Cedars-Sinai Medical Center,Synthetic Biologics, Inc.
- Current Assignee Address: US CA Los Angeles US MD Rockville
- Agency: Nixon Peabody LLP
- Agent Linda B. Huber
- International Application: PCT/US2016/025214 WO 20160331
- International Announcement: WO2016/161085 WO 20161006
- Main IPC: A61K31/366
- IPC: A61K31/366 ; A61P1/14 ; A61K9/00 ; A61K45/06 ; A61K9/24 ; A61K9/16

Abstract:
The present invention relates to, in part, methods for the treatment of methanogen-associated disorders such as, for example, Irritable Bowel Syndrome (IBS) using at least one anti-methanogenic lovastatin analog or derivative. In addition, modified-release formulations comprising at least one anti-methanogenic lovastatin analog or derivative are provided which release the anti-methanogenic lovastatin analog or derivative in the gastrointestinal tract.
Public/Granted literature
- US20180289667A1 ANTI-METHANOGENIC LOVASTATIN ANALOGS OR DERIVATIVES AND USES THEREOF Public/Granted day:2018-10-11
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