Invention Grant
- Patent Title: One-bead-two-compound macrocyclic library and methods of preparation and use
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Application No.: US15947587Application Date: 2018-04-06
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Publication No.: US10738082B2Publication Date: 2020-08-11
- Inventor: Jianfeng Cai , Yan Shi
- Applicant: University of South Florida
- Applicant Address: US FL Tampa
- Assignee: University of South Florida
- Current Assignee: University of South Florida
- Current Assignee Address: US FL Tampa
- Agency: Fish & Richardson P.C.
- Main IPC: C07K7/54
- IPC: C07K7/54 ; A61K38/12 ; A61P35/00 ; C40B40/10 ; C40B50/16 ; C07K1/04 ; A61K38/00 ; C07K7/06 ; C07K17/14 ; G01N33/566 ; C40B30/04
Abstract:
A one-bead-two-compound combinatorial synthesis technique provides libraries of macrocyclic peptidomimetic compounds and compositions with use as ligands for the Ephrin type-A receptor 2 (EphA2). The one-bead-two-compound technique and libraries of macrocyclic compounds are useful as research tools in drug discovery and/or to treat or prevent a range of diseases or disorders.
Public/Granted literature
- US20180291063A1 ONE-BEAD-TWO-COMPOUND MACROCYCLIC LIBRARY AND METHODS OF PREPARATION AND USE Public/Granted day:2018-10-11
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