- Patent Title: Compositions and methods for treating and preventing inflammation
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Application No.: US15507407Application Date: 2015-09-08
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Publication No.: US10738122B2Publication Date: 2020-08-11
- Inventor: Przemyslaw Sapieha , Normand Beaulieu
- Applicant: RSEM, LIMITED PARTNERSHIP
- Applicant Address: CA Montreal
- Assignee: RSEM, LIMITED PARTNERSHIP
- Current Assignee: RSEM, LIMITED PARTNERSHIP
- Current Assignee Address: CA Montreal
- Agency: Klarquist Sparkman, LLP
- International Application: PCT/CA2015/050862 WO 20150908
- International Announcement: WO2016/033699 WO 20160310
- Main IPC: A61K47/68
- IPC: A61K47/68 ; C12N15/62 ; C07K16/28 ; A61K31/713 ; A61K31/7105 ; C07K14/71 ; C07K16/22 ; A61K39/395 ; C12N15/113 ; A61K39/00 ; A61K38/00
Abstract:
The present invention provides novel compounds compositions and methods for (i) treating or preventing inflammation; and (ii) preventing or reducing hyperactivation of innate immune response, by inhibiting NRP1-dependent cell-signaling. Also provided are compounds, composition, and methods of specifically inhibiting SEMA3A-mediated cell signaling.
Public/Granted literature
- US20170283502A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING INFLAMMATION Public/Granted day:2017-10-05
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