Invention Grant
- Patent Title: Anti-FLT-1 antibodies in treating bronchopulmonary dysplasia
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Application No.: US15564969Application Date: 2016-04-07
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Publication No.: US10738123B2Publication Date: 2020-08-11
- Inventor: Dennis Keefe , Steven Abman , Gregory Seedorf
- Applicant: SHIRE HUMAN GENETIC THERAPIES, INC. , THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
- Applicant Address: US MA Lexington US CO Denver
- Assignee: Shire Human Genetic Therapies, Inc.,The Regents of the University of Colorado, A Body Corporate
- Current Assignee: Shire Human Genetic Therapies, Inc.,The Regents of the University of Colorado, A Body Corporate
- Current Assignee Address: US MA Lexington US CO Denver
- Agency: Proskauer Rose LLP
- Agent Fangli Chen; Julio J. Mendez.
- International Application: PCT/US2016/026420 WO 20160407
- International Announcement: WO2016/164567 WO 20161013
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K9/00 ; A61K39/00 ; A23L33/10 ; A61K31/07 ; A61K31/56 ; A61K33/00 ; A61K39/395 ; A61K45/06

Abstract:
The present invention provides, among other things, methods and compositions for treating chronic lung disorders, in particular, bronchopulmonary dysplasia (BPD). In some embodiments, a method according to the present invention includes administering to an individual who is suffering from or susceptible to BPD an effective amount of an anti-Flt-1 antibody, or antigen binding fragment thereof, such that at least one symptom or feature of BPD is reduced in intensity, severity, or frequency, or has delayed onset.
Public/Granted literature
- US20180072805A1 ANTI-FLT-1 ANTIBODIES IN TREATING BRONCHOPULMONARY DYSPLASIA Public/Granted day:2018-03-15
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