The present disclosure provides a resin composition, a cured photoresist and a display panel. The resin composition includes an initiator, at least one multifunctional monomer, a resin, a solvent, and an agent; wherein the multifunctional monomer comprises a monomer compound with the secondary amine group. Through the above-mentioned method, the present disclosure can realize the low-temperature curing of a photoresist, and can further reduce the phenomenon of high-temperature yellowing of the organic flat layer material during the subsequent curing process, and the high-temperature deformation of the substrate can be avoided in the application of flexible displays.