Invention Grant
- Patent Title: Methods of producing nor-opioid and nal-opioid benzylisoquinoline alkaloids
-
Application No.: US16127084Application Date: 2018-09-10
-
Publication No.: US10738335B2Publication Date: 2020-08-11
- Inventor: Christina D. Smolke , Catherine Thodey , Isis Trenchard
- Applicant: Antheia, Inc.
- Applicant Address: US CA Menlo Park
- Assignee: Antheia, Inc.
- Current Assignee: Antheia, Inc.
- Current Assignee Address: US CA Menlo Park
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: C12P17/18
- IPC: C12P17/18 ; C12N9/02 ; C12N9/06 ; C12N9/04 ; C12N9/14 ; C12N15/85 ; C12P17/12 ; C12N9/90
Abstract:
A method of demethylizing an opioid to a nor-opioid is provided. The method comprises contacting an opioid with at least one enzyme. Contacting the opioid with the at least one enzyme converts the opioid to a nor-opioid. A method of converting a nor-opioid to a nal-opioid is provided. The method comprises contacting a nor-opioid with at least one enzyme. Contacting the nor-opioid with the at least one enzyme converts the nor-opioid to a nal-opioid.
Public/Granted literature
- US20190144900A1 METHODS OF PRODUCING NOR-OPIOID AND NAL-OPIOID BENZYLISOQUINOLINE ALKALOIDS Public/Granted day:2019-05-16
Information query
