Invention Grant
- Patent Title: Method for testing and screening p38 map kinase modifiers
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Application No.: US15936027Application Date: 2018-03-26
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Publication No.: US10738345B2Publication Date: 2020-08-11
- Inventor: Gideon Dreyfuss , Mumtaz Kasim
- Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- Applicant Address: US PA Philadelphia
- Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- Current Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
- Current Assignee Address: US PA Philadelphia
- Agency: Pearl Cohen Zedek Latzer Baratz LLP
- Agent Mark S. Cohen
- Main IPC: C12Q1/48
- IPC: C12Q1/48 ; C07D241/04 ; A61K31/496
Abstract:
This invention provides methods for treating diseases associated with elevated p38 mitogen-activated protein kinase activity. Moreover, the invention provides methods for testing a candidate compound for a p38 mitogen-activated protein kinase modifying activity by calculating the level of relocalization of an SMN complex component from the cytoplasm to the nucleus of a cell. Additionally, the invention provides a kit and a system for calculating the same.
Public/Granted literature
- US20190071710A1 METHOD FOR TESTING AND SCREENING P38 MAP KINASE MODIFIERS Public/Granted day:2019-03-07
Information query
