Invention Grant
- Patent Title: Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
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Application No.: US14735477Application Date: 2015-06-10
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Publication No.: US10738358B2Publication Date: 2020-08-11
- Inventor: Mathias Ehrich , Anders Olof Herman Nygren
- Applicant: Sequenom, Inc.
- Applicant Address: US CA San Diego
- Assignee: Sequenom, Inc.
- Current Assignee: Sequenom, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6883 ; C12Q1/6804 ; C12Q1/6809 ; C12Q1/6888 ; C12Q1/6806 ; C12Q1/6879 ; G01N33/53
Abstract:
Provided are compositions and processes that utilize genomic regions differentially methylated between a mother and her fetus to separate, isolate or enrich fetal nucleic acid from a maternal sample. The compositions and processes described herein are useful for non-invasive prenatal diagnostics, including the detection of chromosomal aneuploidies.
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