Invention Grant
- Patent Title: Method for assisting detection of alzheimer'S disease or mild cognitive impairment
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Application No.: US15557752Application Date: 2016-03-11
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Publication No.: US10738360B2Publication Date: 2020-08-11
- Inventor: Hidetoshi Tahara , Masayasu Matsumoto , Yu Ninose
- Applicant: HIROSHIMA UNIVERSITY
- Applicant Address: JP Higashihiroshima-Shi
- Assignee: HIROSHIMA UNIVERSITY
- Current Assignee: HIROSHIMA UNIVERSITY
- Current Assignee Address: JP Higashihiroshima-Shi
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@9e47a3
- International Application: PCT/JP2016/057827 WO 20160311
- International Announcement: WO2016/148073 WO 20160922
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6883 ; G01N33/50

Abstract:
Disclosed is a method for assisting the detection of Alzheimer's disease or mild cognitive impairment, the method for assisting the highly accurate detection of Alzheimer's disease or mild cognitive impairment. In the method for assisting the detection of Alzheimer's disease or mild cognitive impairment, the amount of at least one miRNA selected from miR-122, miR-144, let-7f, miR-128-3p and miR-107 contained in a test sample separated from a living body is used as an indicator. A larger amount of miR-122 than that in a healthy individual, or a smaller amount of at least one miRNA selected from miR-144, let-7f, miR-128-3p and miR-107 than that in a healthy individual is indicative that the living body is more likely to have developed Alzheimer's disease or mild cognitive impairment.
Public/Granted literature
- US20180067132A1 METHOD FOR ASSISTING DETECTION OF ALZHEIMER'S DISEASE OR MILD COGNITIVE IMPAIRMENT Public/Granted day:2018-03-08
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